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Human-specific cartilage changes and joint-disease risk

Atualização 1 de 1Mais recente15/11, 6:53 UTCDia 1
Human cartilage has less water-holding sugar. Genes offer a clue why
A human–ape comparison links altered gene regulation to lower levels of cartilage’s water-holding GAGs. How much that contributes to osteoarthritis remains unresolved.
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Fonte mais antigaHayadan - Hayadan1/10, 6:33 UTC
O que sabíamos inicialmente
- 8Joint types with lower human GAG levels
- 42Human cartilage donors reported by researchers
- 7Great-ape individuals in the tissue comparison

Quem noticiou

Quem noticiou

15 órgãos · 19 fontes

1 de 15 já tinham noticiado até este momento

jpost.comPrimeiro a noticiarjpost.com · 14/11, 10:48 UTC1
1. Israeli study finds why humans suffer from joint pain while apes stay agile - The Jerusalem Post14/11 UTC
Naturenature.com3
PubMed Central (PMC)nih.gov3
GitHubgithub.com1
1. GokhmanLabOrganization/the_gene_regulatory_evolution_of_the_human_skeleton
Hayadan - Hayadanhayadan.com1
1. The Evolution of Cartilage: Why Human Joints Are Prone to Erosion1/10 UTC
McGill Law Journalmcgill.ca1
1. What makes us human? A first atlas of functional DNA changes offers new clues | Newsroom - McGill University
PLOSplos.org1
1. Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis | PLOS One
Technion - Israel Institute of Technologytechnion.ac.il1
1. The gene-regulatory evolution of the human skeleton

Quem está envolvido

Quem está envolvido

Pessoas

David Gokhmanresearcher
Fumitaka Inoueresearcher (ORCID 0000-0003-0657-434X)
Yizhi Yanresearcher (ORCID 0000-0003-4054-3125)

Organizações

Kyoto Universitynational university located in Kyoto, Japan
NatureBritish scientific journal since 1869
Weizmann Institute of Scienceresearch institute in Rehovot, Israel

Locais

Kyoto
Rehovot