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Human-specific cartilage changes and joint-disease risk

Update 1 van 1Nieuwste15 nov, 6:53 UTCDag 1
Human cartilage has less water-holding sugar. Genes offer a clue why
A human–ape comparison links altered gene regulation to lower levels of cartilage’s water-holding GAGs. How much that contributes to osteoarthritis remains unresolved.
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Vroegste bronHayadan - Hayadan1 okt, 6:33 UTC
Wat we eerst wisten
- 8Joint types with lower human GAG levels
- 42Human cartilage donors reported by researchers
- 7Great-ape individuals in the tissue comparison

Wie meldde het

Wie meldde het

15 media · 19 bronnen

1 van de 15 hadden op dit moment bericht

jpost.comMeldde het als eerstejpost.com · 14 nov, 10:48 UTC1
1. Israeli study finds why humans suffer from joint pain while apes stay agile - The Jerusalem Post14 nov UTC
Naturenature.com3
PubMed Central (PMC)nih.gov3
GitHubgithub.com1
1. GokhmanLabOrganization/the_gene_regulatory_evolution_of_the_human_skeleton
Hayadan - Hayadanhayadan.com1
1. The Evolution of Cartilage: Why Human Joints Are Prone to Erosion1 okt UTC
McGill Law Journalmcgill.ca1
1. What makes us human? A first atlas of functional DNA changes offers new clues | Newsroom - McGill University
PLOSplos.org1
1. Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis | PLOS One
Technion - Israel Institute of Technologytechnion.ac.il1
1. The gene-regulatory evolution of the human skeleton

Wie erbij betrokken is

Wie erbij betrokken is

Personen

David Gokhmanresearcher
Fumitaka Inoueresearcher (ORCID 0000-0003-0657-434X)
Yizhi Yanresearcher (ORCID 0000-0003-4054-3125)

Organisaties

Kyoto Universitynational university located in Kyoto, Japan
NatureBritish scientific journal since 1869
Weizmann Institute of Scienceresearch institute in Rehovot, Israel

Plaatsen

Kyoto
Rehovot